Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-chloro-, ethyl ester - Names and Identifiers
Name | ethyl7-chlorolH-imidazo[1,2-a]pyridine-2-carboxylate
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Synonyms | BUTTPARK 15450-01 Ethyl 6-chloroimidazo[1,2-a]pyridine-2-carboxylate ETHYL 6-CHLOROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLATE ethyl 6-chloroimidazo[1,2-a]pyridine-2-carboxylate ethyl7-chlorolH-imidazo[1,2-a]pyridine-2-carboxylate 6-CHLOROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER 6-chloro-2-imidazo[1,2-a]pyridinecarboxylic acid ethyl ester 6-BROMO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-chloro-, ethyl ester
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CAS | 67625-38-1
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EINECS | 604-604-1 |
InChI | InChI=1/C10H9ClN2O2/c1-2-15-10(14)8-6-13-5-7(11)3-4-9(13)12-8/h3-6H,2H2,1H3 |
Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-chloro-, ethyl ester - Physico-chemical Properties
Molecular Formula | C10H9ClN2O2
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Molar Mass | 224.64 |
Density | 1.36±0.1 g/cm3(Predicted) |
Melting Point | 112-114° |
pKa | 1.67±0.50(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.613 |
Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-chloro-, ethyl ester - Risk and Safety
Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-chloro-, ethyl ester - Introduction
ethyl7-chlorolH-imidazo[1,2-a]pyridine-2-carboxylate is an organic compound whose chemical formula is C11H8ClN3O2.
Nature:
-Appearance: ethyl7-chlorolH-imidazo[1,2-a]pyridine-2-carboxylate as a colorless crystalline solid.
-Solubility: It has good solubility in polar solvents, such as alcohols, esters, methanol and dimethyl sulfoxide.
-Melting point: Its melting point is about 156-158°C.
-Stability: ethyl7-chlorolH-imidazo[1,2-a]pyridine-2-carboxylate is relatively stable under conventional experimental conditions.
Use:
ethyl7-chlorolH-imidazo[1,2-a]pyridine-2-carboxylate are mainly used as intermediates in organic synthesis. It can be used to synthesize various compounds containing imidazole and pyridine structures, such as drugs, pesticides and dyes. Due to its availability and diversity in organic reactions, it has a wide range of applications in fields such as medicinal chemistry and pesticide chemistry.
Preparation Method:
The preparation of ethyl7-chlorolH-imidazo[1,2-a]pyridine-2-carboxylate can be achieved by a variety of methods. One of the commonly used methods is to treat 6-chloroimidazo [1,2-A] pyridine with hypochlorous acid, and further react with acetic anhydride under suitable conditions to obtain the target product.
Safety Information:
When using the ethyl7-chlorolH-imidazo[1,2-a]pyridine-2-carboxylate, it should strictly follow the laboratory procedures. It may cause irritation to the eyes, skin and respiratory tract, so contact with eyes and skin must be avoided. Appropriate personal protective equipment such as lab gloves, goggles and protective masks shall be provided during use. At the same time, it should be ensured that the operation is carried out under good ventilation to prevent the generation of harmful gases. If exposed or inhaled, seek medical attention promptly.
Last Update:2024-04-09 21:11:58